Guest Societies

ASMB is pleased to welcome the following Guest Societies who will host sessions at the ASMB Biennial Meeting. The detailed schedule of speakers can be found in the ASMB Program.


 

Sunday, October 14, 10:00am

Guest Symposium I:  TERMIS

TERMIS brings together the international community of persons engaged or interested in the field of tissue engineering and regenerative medicine, promoting International Education and Collaboration for the Advancement of Tissue Engineering & Regenerative Medicine. This TERMIS-sponsored session will feature young and international scholars that work at the interface of tissue engineering and matrix biology. Topics covered will have a range of applications but will focus at this interface.

Guest Symposium I:  Alport Syndrome Foundation

This Symposium, sponsored by the Alport Syndrome Foundation, features three invited speakers, all of whom are physician-scientists.  They will present new data focused on type IV collagen biochemistry, glomerular basement membrane composition and architecture, and clinical aspects of the disease.  In addition, two short talks will be chosen from submitted abstracts. This will be an excellent opportunity to meet other Alport syndrome researchers and learn about the latest discoveries regarding this important extracellular matrix disease.

Guest Symposium I: The Histochemical Society

The Histochemical Society is a scientific society dedicated to the development and application of new technologies in molecular pathology and cell biology and to the education of scientists in the use of these technologies to investigate normal and diseased cells and tissues. The goal of this session is to provide attendees with the background required to perform high-quality, immunohistochemistry, microscopy, and quantitation of digital images to provide information about the mechanisms whereby the ECM provides critical cues for stromal and immune cells in health and disease.
 

Monday, October 15, 4:30pm

Guest Symposium IV:  Matrix Biology Ireland

Matrix Biology Ireland (MBI) was established in 2013 and we are running annual meetings since 2014. MBI aspires to promote and consolidate scientific interest and expertise in extracellular matrix (ECM) research and to link with the international scientific community of Matrix Biology. This session will provide a flavour of ECM-based research in Ireland and examples of branching out with international collaborators.

 


 

Special Interest Sessions

ASMB is pleased to offer the following  Special Interest Sessions led and organized by trainees.

Sunday, October 14, 2:45-4:15pm

SIS 1: Extracellular Vesicles- The next SMALL thing

Organizer: Shyam Kumar Bandari, University of Alabama at Birmingham

Extracellular vesicles (EV’s) are a cell derived heterogeneous group of membranous lipid vesicles ranging in size from 30-1000 nm. Depending on their origin, EV’s are classified into exosomes and microvesicles. Exosomes are formed by the inward budding of endosomal membrane and are 30-150 nm in size. Microvesicles are derived from budding of the plasma membrane and are 150-1000 nm in size. Extracellular vesicles are released into the extracellular space, are present in biological fluids and can regulate many physiological and pathological processes. Carrying proteins, DNA, RNA, mRNA and miRNA from their cell or origin, they travel locally or distally in the fluid compartments of the body, dock with recipient cells and deliver their contents. This EV-mediated transfer of information has emerged as a newly understood major mechanism of intercellular communication. Mounting body of literature suggests that EVs play a key role in cancer for example, they regulate cell signaling, transcription, immune regulation and aid in formation of pre-metastatic niches. In addition, EV’s have been shown to play seminal roles in cardiovascular, neurodegenerative and infectious diseases. Additionally, EVs are emerging as a rich source of biomarkers for disease prognosis and staging. EVs are also being exploited as potential devices for delivery of drugs. The overall goal of this session is to provide the basic understanding of EVs and their roles in disease progression.

 

Tuesday, October 16, 2:00-3:30pm

Emerging Non-Canonical Intracellular Roles of Extracellular Matrix proteins

Organizer: Davy Vanhoutte, Cincinnati Children’s Hospital Medical Center

Although the primary site of action of extracellular matrix proteins (ECM) is outside the cell, recent reports challenge this paradigm by providing proof that ECM proteins can reside and function inside various intracellular compartments. Collectively, these studies strongly support the localization and active roles of various ECM proteins that alter endoplasmic reticulum (ER) stress, mitochondrial function, autophagy, metabolism or transcription, whereas others were shown to actively chaperone extracellular proteins into the cell once secreted during various pathological conditions.

Hence, this session will first provide a brief status update on the intracellular localization and roles of established ECM proteins, as well as the challenges that come with investigating this area of matrix biology. Next, the presenters of this session will highlight how their previous and ongoing studies illustrate diverse routes by which specific ECM proteins – including Thrombospondins, SPARC and MMPs- can reside inside the cell, and direct unexpected intracellular functions. Finally, the presenters will discuss how these newly discovered intracellular functions contribute to tissue homeostasis and disease such as heart, skeletal muscle and kidney disease as well as cancer.

 

Wednesday, October 17, 11:00am – 12:30pm

SIS 3: Trainee Led Session: The development and use of 3D systems to investigate biological function

Organizer: Reut Shainer, National Institutes of Dental and Craniofacial Research, NIH

Description: 3D cell culture systems have gained increasing interest in the last 2 decades as a platform to mimic the native environment of the cells that favor cell-cell interaction and ECM support.

They have become a well-accepted tool in the fields of tissue engineering, cancer research and drug discovery and for this reason a broad range of biomaterials have been developed.

This session will bring together research presentations that highlight the field of 3D cell cultures related to matrix biology.

Invited Talk: 3D organoids of skeletal stem cell in vitro and in vivo, Pam Robey, NIH NIDCR